Southern Research, for which we are an agent, undertakes nonclinical efficacy evaluation studies of infectious disease vaccines and therapeutic drugs. They have established in vivo infection models for a variety of viruses and are capable of conducting tests at BSL2 or BSL3. In addition to efficacy evaluation, they also undertake nonclinical safety studies in accordance with GLP and immunogenicity tests (analysis of clinical samples) in accordance with GCLP.
For testing requests or inquiries regarding Southern Research, please feel free to contact us.
Efficacy evaluation and safety studies of infectious disease vaccines and therapeutic drugs
About Southern Research
Southern Research features:
Broad pathogen expertise (influenza, COVID-19, monkeypox, flaviviruses including chikungunya, dengue, and Zika)
Small animal (rats, mice, hamsters, ferrets, etc.) ~ Primate (NHPs) infectious disease models
Extensive experience in handling Tier 1 Select Agents (e.g. MPOX)
Research conducted in compliance with FDA animal regulations
Service
Non-clinical safety studies (GLP) :
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General toxicity studies (small and large animals)
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Biodistribution and pharmacokinetic studies
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Immunogenicity studies
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Neurovirulence
Clinical trial sample analysis (GCLP) :
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Vaccine Immunogenicity Studies
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Microneutralization Assay (MA )
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Focus Reduction Neutralization Test (FRNT)
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Infection prevention effect (viral load measurement)
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PCR
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RT-PCR
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TCID50
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Non-clinical safety studies (GLP) :
-
General toxicity studies (small and large animals)
-
Biodistribution and pharmacokinetic studies
-
Immunogenicity studies
-
Neurovirulence
Clinical trial sample analysis (GCLP) :
-
Vaccine Immunogenicity Studies
-
Microneutralization Assay (MA )
-
Focus Reduction Neutralization Test (FRNT)
-
-
Infection prevention effect (viral load measurement)
-
PCR
-
RT-PCR
-
TCID50
-